Monday, June 18, 2018

Mitochondrial musings


This is my maternal ancestry, highlighted in yellow.

This is the path, through these women, that my mitochandrial DNA took across the landscape of this county.

Letty Durham is my "Most Distant Known" maternal ancestor, following my mother's line. She was born about 1744, probably in North Carolina. In 1776, when the Revolutionary War began, she was about 32 years old and had about 5 children (the birth dates of her children are not certain). She had a total of about 10 children by 1790.



Some time after 1790 she migrated from North Carolina (or possibly Georgia) to Kentucky, with her children, through the Cumberland Gap and lived the rest of her life in Kentucky.

The "Wilderness Road" through the Cumberland Gap - my people took a sharp right after they passed through the "Gap" and travelled up the Licking River.

The woman at the bottom of this tree, Dora Howard, is my mother's maternal grandmother. She was born in 1903 in Magoffin County, Kentucky.

In the family tree, above, you may notice the places "Licking River" and "Middle Fork". These are not towns, they are farms built by the banks of the Licking River, and the "Middle Fork" of the Licking River, in the mountains of eastern Kentucky in what became Magoffin County in 1860.




My mother was born in her grandmother's house, by the banks of the middle fork of the Licking River, in 1939, near a place called Gullett. She spent the first few years of her life there. Her parents (Josephine Risner and Seville Gose) moved to Ada, in Hardin County, Ohio before 1944.

Maureen Gose, about 1941.


Class, and teacher, at her one-room schoolhouse in Magoffin County, Kentucky. She circled herself in the left of the picture.

Maureen Gose, by the front porch in Ada, Ohio, 1962.

Christmas, 1970's, Ada, Ohio. Maureen Gose is seated in front.


Dora Howard (in back), John Henry Risner (right). Maureen Gose (white hat).

Dora Howard, her husband (John Henry Risner) and their other two children moved to Winchester, in Clark County, Kentucky.



Dora Howard, 1970's, Winchester, KY.




I used the following website, along with a Chrome extension called PhyloTree MT AddOn, to plug my FamilytreeDNA mitochondrial test results into the Haplotype tree.

Phylotree.org

My results:

http://www.phylotree.org/tree/R0.htm

This is a  a link to the results for my FamilyTreeDNA test kit #747482 on Phylotree.org for my mitochondrial DNA.

If you use your browser to search the page for T16189C! it will get twelve "hits".

This site maps a haplotype on the "phylogenetic tree", showing you where your mitochondrial haplotype is in the larger tree.

Unfortunatly for me my haplotype, H1-T16189C!, is a back-mutation that has occured at at least 12 points in the tree. Since my mutation begins with H1, I think I can discount all but 5 of the possible hits.

The particular version of the tree I used for this is current as af 18 June 2018 (this is the day I ran my analysis.)

PhyloTree.org - mtDNA tree Build 17 (18 Feb 2016): subtree R0

My haplotype is under subtree RO-H1, it could be one of these five:

H1a-T16189C!
H1a6-T16189C!
H1c3b-T16189C!
H1j9-T16189C! (listed as unstable)
H1ap1-T16189C!

I really have no idea which it may be, or if I am on the right track in my understanding of how the mutation mapping works.

I belong to the Mitochondrial DNA Haplogroup H & HV Project on FamilyTreeDNA and submited this as a question. I hope to add the answer to my website soon.

Other links to information (actually, more questions) about this Haplotype:

https://www.geni.com/discussions/160517

https://www.eupedia.com/forum/threads/35184-H1-T16189C!-Help-!!

https://www.snpedia.com/index.php/Gs1006

http://www.thecid.com/mtdnatree/ppl/c/5/d420cc4cd3c1d579949b3f3745c.html

https://www.ncbi.nlm.nih.gov/pubmed/25208176

http://www.ianlogan.co.uk/sequences_by_group/h1-t16189c_genbank_sequences.htm

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